No association of coronary artery disease with x-chromosomal variants in comprehensive international meta-analysis

No association of coronary artery disease with x-chromosomal variants in comprehensive international meta-analysis

In recent years, genome-wide association studies have identified 58 independent risk loci for coronary artery disease (CAD) on the autosome. However, due to the sex-specific data structure of the X chromosome, it has been excluded from most of these analyses. While females have 2 copies of chromosom...

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Detalles Bibliográficos
Autores principales: Loley, C, Alver, M, Assimes, T, Bjonnes, A, Goel, A, Gustafsson, S, Hernesniemi, J, Hopewell, J, Kanoni, S, Kleber, M, Lau, K, Lu, Y, Lyytikäinen, L, Nelson, C, Nikpay, M, Qu, L, Salfati, E, Scholz, M, Tukiainen, T, Willenborg, C, Won, H, Zeng, L, Zhang, W, Anand, S, Beutner, F, Bottinger, E, Clarke, R, Dedoussis, G, Do, R, Esko, T, Eskola, M, Farrall, M, Gauguier, D, Giedraitis, V, Granger, C, Hall, A, Hamsten, A, Hazen, S, Huang, J, Kähönen, M, Kyriakou, T, Laaksonen, R, Lind, L, Lindgren, C, Magnusson, P, Marouli, E, Mihailov, E, Morris, A, Nikus, K, Pedersen, N, Rallidis, L, Salomaa, V, Shah, S, Stewart, A, Thompson, J, Zalloua, P, Chambers, J, Collins, R, Ingelsson, E, Iribarren, C, Karhunen, P, Kooner, J, Lehtimäki, T, Loos, R, März, W, McPherson, R, Metspalu, A, Reilly, M, Ripatti, S, Sanghera, D, Thiery, J, Watkins, H, Deloukas, P, Kathiresan, S, Samani, N, Schunkert, H, Erdmann, J, König, I
Formato: Journal article
Lenguaje:English
Publicado: Springer Nature 2016

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