Mathematical modelling of the ischaemic heart
Recent advances in high performance computing combined with increasing knowledge of them kinetics of biochemical reactions and transport processes have allowed us to develop mathematical models that describe various aspects of cardiac physiology. These models include both single cell and three-dimen...
| Những tác giả chính: | , , , |
|---|---|
| Định dạng: | Journal article |
| Được phát hành: |
2001
|
| _version_ | 1826271755099963392 |
|---|---|
| author | Mulquiney, P Smith, N Clarke, K Hunter, P |
| author_facet | Mulquiney, P Smith, N Clarke, K Hunter, P |
| author_sort | Mulquiney, P |
| collection | OXFORD |
| description | Recent advances in high performance computing combined with increasing knowledge of them kinetics of biochemical reactions and transport processes have allowed us to develop mathematical models that describe various aspects of cardiac physiology. These models include both single cell and three-dimensional tissue models that simulate important features of cardiac electrophysiology, mechanics, and metabolism. We have begun to couple these models with the goal of creating a fully integrated cardiac model that can describe the pathophysiology of the ischaemic heart. Here we present an outline of this work. |
| first_indexed | 2024-03-06T22:01:42Z |
| format | Journal article |
| id | oxford-uuid:4ed09b87-d881-41fc-89a9-f52cc6c7dd44 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T22:01:42Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:4ed09b87-d881-41fc-89a9-f52cc6c7dd442022-03-26T16:03:24ZMathematical modelling of the ischaemic heartJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4ed09b87-d881-41fc-89a9-f52cc6c7dd44Department of Computer Science2001Mulquiney, PSmith, NClarke, KHunter, PRecent advances in high performance computing combined with increasing knowledge of them kinetics of biochemical reactions and transport processes have allowed us to develop mathematical models that describe various aspects of cardiac physiology. These models include both single cell and three-dimensional tissue models that simulate important features of cardiac electrophysiology, mechanics, and metabolism. We have begun to couple these models with the goal of creating a fully integrated cardiac model that can describe the pathophysiology of the ischaemic heart. Here we present an outline of this work. |
| spellingShingle | Mulquiney, P Smith, N Clarke, K Hunter, P Mathematical modelling of the ischaemic heart |
| title | Mathematical modelling of the ischaemic heart |
| title_full | Mathematical modelling of the ischaemic heart |
| title_fullStr | Mathematical modelling of the ischaemic heart |
| title_full_unstemmed | Mathematical modelling of the ischaemic heart |
| title_short | Mathematical modelling of the ischaemic heart |
| title_sort | mathematical modelling of the ischaemic heart |
| work_keys_str_mv | AT mulquineyp mathematicalmodellingoftheischaemicheart AT smithn mathematicalmodellingoftheischaemicheart AT clarkek mathematicalmodellingoftheischaemicheart AT hunterp mathematicalmodellingoftheischaemicheart |