A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages

Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and...

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Hlavní autoři: Chambers, KL, Myerscough, MR, Byrne, HM
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2023