From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates

The synthesis of three stereoisomeric cis- and trans-5-azidomethyl- tetrahydrofuran-2-carboxylates in which a ketal-protected cis-diol unit is present is described. The monomers undergo efficient oligomerisation to tetrameric carbopeptoids in which the diol protection facilitates ready purification...

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Main Authors: Long, D, Hungerford, N, Smith, M, Brittain, D, Marquess, D, Claridge, T, Fleet, G
Format: Journal article
Language:English
Published: 1999
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author Long, D
Hungerford, N
Smith, M
Brittain, D
Marquess, D
Claridge, T
Fleet, G
author_facet Long, D
Hungerford, N
Smith, M
Brittain, D
Marquess, D
Claridge, T
Fleet, G
author_sort Long, D
collection OXFORD
description The synthesis of three stereoisomeric cis- and trans-5-azidomethyl- tetrahydrofuran-2-carboxylates in which a ketal-protected cis-diol unit is present is described. The monomers undergo efficient oligomerisation to tetrameric carbopeptoids in which the diol protection facilitates ready purification by chromatography which augurs well for the formation of homogeneous higher polymers.
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spelling oxford-uuid:4ed9030d-1e64-4337-8d72-2517cd4d3a272022-03-26T16:03:38ZFrom sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylatesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4ed9030d-1e64-4337-8d72-2517cd4d3a27EnglishSymplectic Elements at Oxford1999Long, DHungerford, NSmith, MBrittain, DMarquess, DClaridge, TFleet, GThe synthesis of three stereoisomeric cis- and trans-5-azidomethyl- tetrahydrofuran-2-carboxylates in which a ketal-protected cis-diol unit is present is described. The monomers undergo efficient oligomerisation to tetrameric carbopeptoids in which the diol protection facilitates ready purification by chromatography which augurs well for the formation of homogeneous higher polymers.
spellingShingle Long, D
Hungerford, N
Smith, M
Brittain, D
Marquess, D
Claridge, T
Fleet, G
From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates
title From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates
title_full From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates
title_fullStr From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates
title_full_unstemmed From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates
title_short From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates
title_sort from sequencamers to foldamers tetrameric furanose carbopeptoids from cis and trans 5 aminomethyl tetrahydrofuran 2 carboxylates
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