Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents
Mathematical models to describe the diffusion of single cryoprotecting agents (CPA) and multiple CPAs in tissue contructs were developed. Fick's law was used to describe single CPA diffusion, and Maxwell-Stefan approach was used to describe multiple CPA transport inside the tissue. The model us...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2002
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| _version_ | 1826271765497643008 |
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| author | Cui, Z Xu, X Urban, J Sambanis, A Nerem, R |
| author_facet | Cui, Z Xu, X Urban, J Sambanis, A Nerem, R |
| author_sort | Cui, Z |
| collection | OXFORD |
| description | Mathematical models to describe the diffusion of single cryoprotecting agents (CPA) and multiple CPAs in tissue contructs were developed. Fick's law was used to describe single CPA diffusion, and Maxwell-Stefan approach was used to describe multiple CPA transport inside the tissue. The model used to to stimulate the CPA loading in articular cartilage and blood vessel constructs. Experimental work using diffusion chambers was carried out to determine the model parameters and verify the models. |
| first_indexed | 2024-03-06T22:01:52Z |
| format | Journal article |
| id | oxford-uuid:4ede0df0-ce4c-4ee3-99b9-addd1a21af10 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:01:52Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:4ede0df0-ce4c-4ee3-99b9-addd1a21af102022-03-26T16:03:44ZCryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agentsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4ede0df0-ce4c-4ee3-99b9-addd1a21af10EnglishSymplectic Elements at Oxford2002Cui, ZXu, XUrban, JSambanis, ANerem, RMathematical models to describe the diffusion of single cryoprotecting agents (CPA) and multiple CPAs in tissue contructs were developed. Fick's law was used to describe single CPA diffusion, and Maxwell-Stefan approach was used to describe multiple CPA transport inside the tissue. The model used to to stimulate the CPA loading in articular cartilage and blood vessel constructs. Experimental work using diffusion chambers was carried out to determine the model parameters and verify the models. |
| spellingShingle | Cui, Z Xu, X Urban, J Sambanis, A Nerem, R Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents |
| title | Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents |
| title_full | Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents |
| title_fullStr | Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents |
| title_full_unstemmed | Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents |
| title_short | Cryopreservation of engineered tissues - Modelling of the transport of cryoprotecting agents |
| title_sort | cryopreservation of engineered tissues modelling of the transport of cryoprotecting agents |
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