Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
Non-insulin-dependent diabetic subjects had abnormally raised in vitro platelet aggregation rates to collagen or ristocetin when thought to be "well-controlled" on diet alone but shown to have raised basal plasma glucose levels. Basal normoglycemia, induced with either ultralente insulin o...
Glavni autori: | , , , |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
1982
|
_version_ | 1826271818247307264 |
---|---|
author | Evans, R Lane, J Holman, R Turner, R |
author_facet | Evans, R Lane, J Holman, R Turner, R |
author_sort | Evans, R |
collection | OXFORD |
description | Non-insulin-dependent diabetic subjects had abnormally raised in vitro platelet aggregation rates to collagen or ristocetin when thought to be "well-controlled" on diet alone but shown to have raised basal plasma glucose levels. Basal normoglycemia, induced with either ultralente insulin or chlorpropamide, was associated with a significant reduction of the enhanced platelet aggregation rates to normal. Some sulfonylurea drugs have been reported to have specific anti-platelet aggregatory properties, but the degree of plasma glucose control is probably more relevant. |
first_indexed | 2024-03-06T22:02:43Z |
format | Journal article |
id | oxford-uuid:4f23f5ac-3185-4d07-bf63-c524b0c55a72 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T22:02:43Z |
publishDate | 1982 |
record_format | dspace |
spelling | oxford-uuid:4f23f5ac-3185-4d07-bf63-c524b0c55a722022-03-26T16:05:21ZInduced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4f23f5ac-3185-4d07-bf63-c524b0c55a72EnglishSymplectic Elements at Oxford1982Evans, RLane, JHolman, RTurner, RNon-insulin-dependent diabetic subjects had abnormally raised in vitro platelet aggregation rates to collagen or ristocetin when thought to be "well-controlled" on diet alone but shown to have raised basal plasma glucose levels. Basal normoglycemia, induced with either ultralente insulin or chlorpropamide, was associated with a significant reduction of the enhanced platelet aggregation rates to normal. Some sulfonylurea drugs have been reported to have specific anti-platelet aggregatory properties, but the degree of plasma glucose control is probably more relevant. |
spellingShingle | Evans, R Lane, J Holman, R Turner, R Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes. |
title | Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes. |
title_full | Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes. |
title_fullStr | Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes. |
title_full_unstemmed | Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes. |
title_short | Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes. |
title_sort | induced basal normoglycemia and altered platelet aggregation in non insulin dependent diabetes |
work_keys_str_mv | AT evansr inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes AT lanej inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes AT holmanr inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes AT turnerr inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes |