Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.

Non-insulin-dependent diabetic subjects had abnormally raised in vitro platelet aggregation rates to collagen or ristocetin when thought to be "well-controlled" on diet alone but shown to have raised basal plasma glucose levels. Basal normoglycemia, induced with either ultralente insulin o...

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Bibliografski detalji
Glavni autori: Evans, R, Lane, J, Holman, R, Turner, R
Format: Journal article
Jezik:English
Izdano: 1982
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author Evans, R
Lane, J
Holman, R
Turner, R
author_facet Evans, R
Lane, J
Holman, R
Turner, R
author_sort Evans, R
collection OXFORD
description Non-insulin-dependent diabetic subjects had abnormally raised in vitro platelet aggregation rates to collagen or ristocetin when thought to be "well-controlled" on diet alone but shown to have raised basal plasma glucose levels. Basal normoglycemia, induced with either ultralente insulin or chlorpropamide, was associated with a significant reduction of the enhanced platelet aggregation rates to normal. Some sulfonylurea drugs have been reported to have specific anti-platelet aggregatory properties, but the degree of plasma glucose control is probably more relevant.
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spelling oxford-uuid:4f23f5ac-3185-4d07-bf63-c524b0c55a722022-03-26T16:05:21ZInduced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4f23f5ac-3185-4d07-bf63-c524b0c55a72EnglishSymplectic Elements at Oxford1982Evans, RLane, JHolman, RTurner, RNon-insulin-dependent diabetic subjects had abnormally raised in vitro platelet aggregation rates to collagen or ristocetin when thought to be "well-controlled" on diet alone but shown to have raised basal plasma glucose levels. Basal normoglycemia, induced with either ultralente insulin or chlorpropamide, was associated with a significant reduction of the enhanced platelet aggregation rates to normal. Some sulfonylurea drugs have been reported to have specific anti-platelet aggregatory properties, but the degree of plasma glucose control is probably more relevant.
spellingShingle Evans, R
Lane, J
Holman, R
Turner, R
Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
title Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
title_full Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
title_fullStr Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
title_full_unstemmed Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
title_short Induced basal normoglycemia and altered platelet aggregation in non-insulin-dependent diabetes.
title_sort induced basal normoglycemia and altered platelet aggregation in non insulin dependent diabetes
work_keys_str_mv AT evansr inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes
AT lanej inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes
AT holmanr inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes
AT turnerr inducedbasalnormoglycemiaandalteredplateletaggregationinnoninsulindependentdiabetes