Increasing LFA-1 expression enhances immune synapse architecture and T cell receptor signaling in Jurkat E6.1 cells

Increasing LFA-1 expression enhances immune synapse architecture and T cell receptor signaling in Jurkat E6.1 cells

The Jurkat E6.1 clone has been extensively used as a powerful tool for the genetic and biochemical dissection of the TCR signaling pathway. More recently, these cells have been exploited in imaging studies to identify key players in immunological synapse (IS) assembly in superantigen-specific conjug...

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Detalhes bibliográficos
Principais autores:	Cassioli, C, Balint, S, Compeer, EB, Felce, JH, Gamberucci, A, Della Bella, C, Felce, SL, Brunetti, J, Valvo, S, Pende, D, D’Elios, MM, Moretta, L, Dustin, ML, Baldari, CT
Formato:	Journal article
Idioma:	English
Publicado em:	Frontiers Media 2021

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