Increasing LFA-1 expression enhances immune synapse architecture and T cell receptor signaling in Jurkat E6.1 cells

The Jurkat E6.1 clone has been extensively used as a powerful tool for the genetic and biochemical dissection of the TCR signaling pathway. More recently, these cells have been exploited in imaging studies to identify key players in immunological synapse (IS) assembly in superantigen-specific conjug...

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Những tác giả chính: Cassioli, C, Balint, S, Compeer, EB, Felce, JH, Gamberucci, A, Della Bella, C, Felce, SL, Brunetti, J, Valvo, S, Pende, D, D’Elios, MM, Moretta, L, Dustin, ML, Baldari, CT
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Frontiers Media 2021