Gene-age interactions in blood pressure regulation: A large-scale investigation with the CHARGE, global BPgen, and ICBP consortia

Although age-dependent effects on blood pressure (BP) have been reported, they have not been systematically investigated in large-scale genome-wide association studies (GWASs). We leveraged the infrastructure of three well-established consortia (CHARGE, GBPgen, and ICBP) and a nonstandard approach (...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Simino, J, Shi, G, Bis, J, Chasman, D, Ehret, G, Gu, X, Guo, X, Hwang, S, Sijbrands, E, Smith, A, Verwoert, G, Bragg-Gresham, J, Cadby, G, Chen, P, Cheng, C, Corre, T, De Boer, R, Goel, A, Johnson, T, Khor, C, Lluís-Ganella, C, Luan, J, Lyytikäinen, L, Nolte, I, Sim, X
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Cell Press 2014