Convergent evolution by cancer and viruses in evading the NKG2D immune response
The natural killer group 2 member D (NKG2D) receptor and its family of NKG2D ligands (NKG2DLs) are key components in the innate immune system, triggering NK, γδ and CD8+ T cell-mediated immune responses. While surface NKG2DL are rarely found on healthy cells, expression is significantly increased in...
Main Authors: | Baugh, R, Khalique, H, Seymour, LW |
---|---|
Format: | Journal article |
Language: | English |
Published: |
MDPI
2020
|
Similar Items
-
Targeting NKG2D ligands in glioblastoma with a bispecific T-cell engager is augmented with conventional therapy and enhances oncolytic virotherapy of glioma stem-like cells
by: Baugh, R, et al.
Published: (2024) -
NKG2D
by: O'Callaghan, C
Published: (2009) -
Structural and energetic aspects of multispecific immune recognition by NKG2D.
by: O'Callaghan, C, et al.
Published: (2003) -
Mechanisms of NKG2D ligand regulation
by: McCarthy, M, et al.
Published: (2013) -
Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60.
by: O'Callaghan, C, et al.
Published: (2001)