Influenza virus inhibits RNA polymerase II elongation.
The influenza virus RNA-dependent RNA polymerase interacts with the serine-5 phosphorylated carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II). It was proposed that this interaction allows the viral RNA polymerase to gain access to host mRNA-derived capped RNA fragments...
Autori principali: | Chan, A, Vreede, F, Smith, M, Engelhardt, O, Fodor, E |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2006
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