Yeast Sen1 helicase protects the genome from transcription-associated instability

Yeast Sen1 helicase protects the genome from transcription-associated instability

Εμφάνιση άλλων εκδόσεων (1)

Sen1 of S.cerevisiae is a known component of the NRD complex implicated in transcription termination on nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts. We now show that Sen1 helicase possesses a wider function by restricting the occurrence of RNA:DNA hybrids that may...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Mischo, H, Gómez-González, B, Grzechnik, P, Rondón, A, Wei, W, Steinmetz, L, Aguilera, A, Proudfoot, N
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Elsevier 2011
Θέματα:	Pathology

Παρόμοια τεκμήρια

Yeast Sen1 helicase protects the genome from transcription-associated instability.
ανά: Mischo, H, κ.ά.
Έκδοση: (2011)

Terminating transcription in yeast: whether to be a 'nerd' or a 'rat'.
ανά: Rondon, A, κ.ά.
Έκδοση: (2008)

Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination.
ανά: Kawauchi, J, κ.ά.
Έκδοση: (2008)

Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast.
ανά: Mischo, H, κ.ά.
Έκδοση: (2013)

Nuclear fate of yeast snoRNA is determined by co-transcriptional Rnt1 cleavage
ανά: Grzechnik, P, κ.ά.
Έκδοση: (2018)

Single-molecule characterization of extrinsic transcription termination by Sen1 helicase
ανά: S. Wang, κ.ά.
Έκδοση: (2019-04-01)

ATPase site architecture and helicase mechanism of an archaeal MCM
ανά: Moreau, M, κ.ά.
Έκδοση: (2007)

Nuclear fate of yeast snoRNA is determined by co-transcriptional Rnt1 cleavage
ανά: Pawel Grzechnik, κ.ά.
Έκδοση: (2018-05-01)

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae.
ανά: Rondón, A, κ.ά.
Έκδοση: (2009)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
ανά: West, S, κ.ά.
Έκδοση: (2008)

Cell-cycle modulation of transcription termination factor Sen1
ανά: Mischo, H, κ.ά.
Έκδοση: (2018)

The Drosophila Helicase MLE Targets Hairpin Structures in Genomic Transcripts.
ανά: Simona Cugusi, κ.ά.
Έκδοση: (2016-01-01)

Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers
ανά: Newman, JA, κ.ά.
Έκδοση: (2020)

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.
ανά: María S Domínguez-Sánchez, κ.ά.
Έκδοση: (2011-12-01)

Aneuploidy Drives Genomic Instability in Yeast
ανά: Sheltzer, Jason Meyer, κ.ά.
Έκδοση: (2013)

Definition of transcriptional pause elements in fission yeast.
ανά: Aranda, A, κ.ά.
Έκδοση: (1999)

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1
ανά: Bassam Abu-Libdeh, κ.ά.
Έκδοση: (2022-03-01)

Terminate and make a loop: regulation of transcriptional directionality
ανά: Tan-Wong, S, κ.ά.
Έκδοση: (2014)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei
ανά: Jackson, D, κ.ά.
Έκδοση: (1998)

DNA repair and genomic instability in yeast aging
ανά: Park, Peter Unnam, 1971-
Έκδοση: (2005)

Gene loops enhance transcriptional directionality
ανά: Tan-Wong, S, κ.ά.
Έκδοση: (2012)

The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage.
ανά: Juan Lafuente-Barquero, κ.ά.
Έκδοση: (2017-12-01)

PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes
ανά: Phong Lan Thao Tran, κ.ά.
Έκδοση: (2017-04-01)

Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in acute myeloid leukemia
ανά: Chi Keung Cheng, κ.ά.
Έκδοση: (2016-04-01)

Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells.
ανά: Gullerova, M, κ.ά.
Έκδοση: (2012)

Rad25p, a DNA helicase subunit of yeast transcription factor TFIIH, is required for promoter escape in vivo.
ανά: Ostapenko, D, κ.ά.
Έκδοση: (2000)

Transcriptional collision between convergent genes in budding yeast.
ανά: Prescott, E, κ.ά.
Έκδοση: (2002)

The transcription cycle of RNA polymerase II in living cells
ανά: Kimura, H, κ.ά.
Έκδοση: (2002)

Similar active genes cluster in specialized transcription factories
ανά: Xu, M, κ.ά.
Έκδοση: (2008)

Werner Syndrome Helicase Is Required for the Survival of Cancer Cells with Microsatellite Instability
ανά: Lorn Kategaya, κ.ά.
Έκδοση: (2019-03-01)

Genomic disorders : [electronic resource] : the genomic basis of disease /
ανά: 190983 Lupski, James R., κ.ά.
Έκδοση: (2006)

Transcriptional interference and gene orientation in yeast: noncoding RNA connections.
ανά: Gullerova, M, κ.ά.
Έκδοση: (2010)

Heat shock drives genomic instability and phenotypic variations in yeast
ανά: Li Shen, κ.ά.
Έκδοση: (2020-08-01)

Genomic Instability and Cellular Senescence: Lessons From the Budding Yeast
ανά: Jee Whu Lee, κ.ά.
Έκδοση: (2021-01-01)

Patterns of Genomic Instability in Interspecific Yeast Hybrids With Diverse Ancestries
ανά: Devin P. Bendixsen, κ.ά.
Έκδοση: (2021-10-01)

Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells
ανά: Simone Lieb, κ.ά.
Έκδοση: (2019-03-01)

Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2.
ανά: Moreira, M, κ.ά.
Έκδοση: (2004)

Transcriptional termination signals for RNA polymerase II in fission yeast.
ανά: Birse, C, κ.ά.
Έκδοση: (1997)

Targeting werner helicase with synthetic lethality in microsatellite instability cancers: Promising therapeutic approaches
ανά: Huanzhang Xie, κ.ά.
Έκδοση: (2024-06-01)

Coupling termination of transcription to messenger RNA maturation in yeast.
ανά: Birse, C, κ.ά.
Έκδοση: (1998)