Yeast Sen1 helicase protects the genome from transcription-associated instability

Yeast Sen1 helicase protects the genome from transcription-associated instability

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Sen1 of S.cerevisiae is a known component of the NRD complex implicated in transcription termination on nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts. We now show that Sen1 helicase possesses a wider function by restricting the occurrence of RNA:DNA hybrids that may...

书目详细资料
Main Authors:	Mischo, H, Gómez-González, B, Grzechnik, P, Rondón, A, Wei, W, Steinmetz, L, Aguilera, A, Proudfoot, N
格式:	Journal article
语言:	English
出版:	Elsevier 2011
主题:	Pathology

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