Yeast Sen1 helicase protects the genome from transcription-associated instability
Sen1 of S.cerevisiae is a known component of the NRD complex implicated in transcription termination on nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts. We now show that Sen1 helicase possesses a wider function by restricting the occurrence of RNA:DNA hybrids that may...
| Hauptverfasser: | , , , , , , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Elsevier
2011
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| Schlagworte: |