HFIP solvent enables alcohols to act as alkylating agents in stereoselective heterocyclization
A new method for the stereoselective synthesis of highly functionalized oxygen heterocycles using allyl or benzyl alcohols as alkylating agents is presented. The process is efficient and atom economic, generating water as the only stoichiometric byproduct. Substoichiometric amounts of Ti(OiPr)4 in H...
Main Authors: | Zhu, Y, Colomer, I, Thompson, A, Donohoe, T |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2019
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