The predictive value of prostate cancer biomarkers depends on age and time to diagnosis: towards a biologically-based screening strategy.

Both benign and malignant prostate diseases elevate total prostate-specific antigen (tPSA), and the incidence of benign disease increases markedly with age. There is evidence, however, that free-to-total PSA ratio (%fPSA) and human kallikrein 2 (hK2) more closely reflect the malignant process. We te...

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Bibliografische gegevens
Hoofdauteurs: Vickers, A, Ulmert, D, Serio, A, Björk, T, Scardino, P, Eastham, J, Berglund, G, Lilja, H
Formaat: Journal article
Taal:English
Gepubliceerd in: 2007

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