Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.

Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.

The Polycomb group (PcG) proteins mediate heritable silencing of developmental regulators in metazoans, participating in one of two distinct multimeric protein complexes, the Polycomb repressive complexes 1 (PRC1) and 2 (PRC2). Although PRC2 has been shown to share target genes with the core transcr...

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Bibliographic Details
Main Authors: Endoh, M, Endo, T, Endoh, T, Fujimura, Y, Ohara, O, Toyoda, T, Otte, A, Okano, M, Brockdorff, N, Vidal, M, Koseki, H
Format: Journal article
Language:English
Published: 2008

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