Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming

Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming

Silencing of the somatic cell type-specific genes is a critical yet poorly understood step in reprogramming. To uncover pathways that maintain cell identity, we performed a reprogramming screen using inhibitors of chromatin factors. Here, we identify acetyl-lysine competitive inhibitors targeting th...

Bibliografski detalji
Glavni autori:	Ebrahimi, A, Sevinç, K, Sevinç, G, Cribbs, A, Philpott, M, Uyulur, F, Morova, T, Dunford, J, Göklemez, S, Arı, Ş, Oppermann, U, Onder, T
Format:	Journal article
Izdano:	Springer Nature 2019

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