Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

Proline is widely known as the only proteogenic amino acid with a secondary amine. In addition to its crucial role in protein structure, the secondary amino acid modulates neurotransmission and regulates the kinetics of signaling proteins. To understand the structural basis of proline import, we sol...

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Bibliographic Details
Main Authors:	Li, HZ, Pike, ACW, Lotsaris, I, Chi, G, Hansen, JS, Lee, SC, Rödström, KEJ, Bushell, SR, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Burgess-Brown, NA, Vandenberg, RJ, Dafforn, TR, Carpenter, EP, Sauer, DB
Format:	Journal article
Language:	English
Published:	Nature Research 2024

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