Pediatric autoimmune epileptic encephalopathies
Pediatric autoimmune epileptic encephalopathies are predominantly characterized by the presence of autoantibodies to the surface of neuronal proteins, for example, N-methyl-d-aspartate (NMDA) receptor antibodies, but also include diseases with non-cell surface antibodies (eg, anti-Hu, glutamic-acid...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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SAGE Publications
2017
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| _version_ | 1826271936128221184 |
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| author | Wright, S Vincent, A |
| author_facet | Wright, S Vincent, A |
| author_sort | Wright, S |
| collection | OXFORD |
| description | Pediatric autoimmune epileptic encephalopathies are predominantly characterized by the presence of autoantibodies to the surface of neuronal proteins, for example, N-methyl-d-aspartate (NMDA) receptor antibodies, but also include diseases with non-cell surface antibodies (eg, anti-Hu, glutamic-acid decarboxylase antibodies). In some cases with distinct clinical and para-clinical features, an autoimmune epileptic encephalopathy can be diagnosed without the presence of an antibody and will also respond favorably to immunotherapy. In this review, we summarize the common presentations of pediatric autoimmune epileptic encephalopathies, treatments, and outcomes, and report recent findings in the field of epilepsy, encephalopathy, and the immune system. |
| first_indexed | 2024-03-06T22:04:36Z |
| format | Journal article |
| id | oxford-uuid:4fb82b43-0972-47d7-9736-2fc0b1452014 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:04:36Z |
| publishDate | 2017 |
| publisher | SAGE Publications |
| record_format | dspace |
| spelling | oxford-uuid:4fb82b43-0972-47d7-9736-2fc0b14520142022-03-26T16:09:04ZPediatric autoimmune epileptic encephalopathiesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4fb82b43-0972-47d7-9736-2fc0b1452014EnglishSymplectic Elements at OxfordSAGE Publications2017Wright, SVincent, APediatric autoimmune epileptic encephalopathies are predominantly characterized by the presence of autoantibodies to the surface of neuronal proteins, for example, N-methyl-d-aspartate (NMDA) receptor antibodies, but also include diseases with non-cell surface antibodies (eg, anti-Hu, glutamic-acid decarboxylase antibodies). In some cases with distinct clinical and para-clinical features, an autoimmune epileptic encephalopathy can be diagnosed without the presence of an antibody and will also respond favorably to immunotherapy. In this review, we summarize the common presentations of pediatric autoimmune epileptic encephalopathies, treatments, and outcomes, and report recent findings in the field of epilepsy, encephalopathy, and the immune system. |
| spellingShingle | Wright, S Vincent, A Pediatric autoimmune epileptic encephalopathies |
| title | Pediatric autoimmune epileptic encephalopathies |
| title_full | Pediatric autoimmune epileptic encephalopathies |
| title_fullStr | Pediatric autoimmune epileptic encephalopathies |
| title_full_unstemmed | Pediatric autoimmune epileptic encephalopathies |
| title_short | Pediatric autoimmune epileptic encephalopathies |
| title_sort | pediatric autoimmune epileptic encephalopathies |
| work_keys_str_mv | AT wrights pediatricautoimmuneepilepticencephalopathies AT vincenta pediatricautoimmuneepilepticencephalopathies |