Opioids depress cortical centers responsible for the volitional control of respiration.
Respiratory depression limits provision of safe opioid analgesia and is the main cause of death in drug addicts. Although opioids are known to inhibit brainstem respiratory activity, their effects on cortical areas that mediate respiration are less well understood. Here, functional magnetic resonanc...
Main Authors: | Pattinson, K, Governo, R, MacIntosh, B, Russell, E, Corfield, DR, Tracey, I, Wise, R |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2009
|
Registos relacionados
-
Opioids modulate the brain activity associated with breath holding: an functional magnetic resonance imaging study
Por: Pattinson, K, et al.
Publicado em: (2009) -
Opioids and the control of respiration.
Por: Pattinson, K
Publicado em: (2008) -
Pharmacological FMRI: measuring opioid effects on the BOLD response to hypercapnia.
Por: Pattinson, K, et al.
Publicado em: (2007) -
Neural activity related to volitional regulation of cortical excitability
Por: Kathy Ruddy, et al.
Publicado em: (2018-11-01) -
Modelling the effect of remifentanil on respiratory variability
Por: Pattinson, K, et al.
Publicado em: (2008)