SUPPRESSION OF IN-VITRO TYPE-17 RESPONSES IN SPA PATIENTS USING SMALL MOLECULE ROR-gamma T INHIBITORS

SUPPRESSION OF IN-VITRO TYPE-17 RESPONSES IN SPA PATIENTS USING SMALL MOLECULE ROR-gamma T INHIBITORS

書目詳細資料
Main Authors:	De Wit, J, Al-Mossawi, M, Huhn, M, Arancibia, C, Powrie, F, Bowness, P
格式:	Journal article
出版:	2014

相似書籍

RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease.
由: de Wit, J, et al.
出版: (2015)

Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases
由: Jiuping Zeng, et al.
出版: (2023-06-01)

BROMODOMAIN INHIBITORS REDUCE TH17-TYPE RESPONSES IN SPONDYLOARTHRITIS IN VITRO
由: Hammitzsch, A, et al.
出版: (2014)

Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.
由: Steven A Saenz, et al.
出版: (2021-01-01)

A ROR1 small molecule inhibitor (KAN0441571C) induced significant apoptosis of ibrutinib‐resistant ROR1+ CLL cells
由: Amineh Ghaderi, et al.
出版: (2021-08-01)

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms
由: Xiao, Sheng, et al.
出版: (2017)

ROR1 is Expressed in Diffuse Large B-Cell Lymphoma (DLBCL) and a Small Molecule Inhibitor of ROR1 (KAN0441571C) Induced Apoptosis of Lymphoma Cells
由: Amineh Ghaderi, et al.
出版: (2020-06-01)

Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
由: Ulf Guendisch, et al.
出版: (2017-01-01)

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.
由: Hammitzsch, A, et al.
出版: (2015)

Immune effector cells in SpA: What are the pathways?
由: Bowness, P, et al.
出版: (2018)

A ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells
由: Amineh Ghaderi, et al.
出版: (2022-10-01)

Identification and validation of a small molecule targeting ROR1 for the treatment of triple negative breast cancer
由: Shradheya R. R. Gupta, et al.
出版: (2023-09-01)

The role of natural killer cells, gamma delta T-cells and other innate immune cells in spondyloarthritis
由: Al-Mossawi, M, et al.
出版: (2013)

The role of natural killer cells, gamma delta T-cells and other innate immune cells in spondyloarthritis.
由: Al-Mossawi, M, et al.
出版: (2013)

TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro
由: Juanbin Yin, et al.
出版: (2023-12-01)

Investigating the potential role of T helper 17 cells among women experiencing overweight and obesity and their possible therapeutic targeting of the RORγt molecule
由: Renad M. Alhamawi, et al.
出版: (2024-11-01)

Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534
由: Xiaohua Xue, et al.
出版: (2021-05-01)

T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORγt expression and function
由: Masaru Shimizu, et al.
出版: (2021-08-01)

An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients
由: Helena Bassolas-Molina, et al.
出版: (2018-10-01)

Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma
由: Feng Leng, et al.
出版: (2025-01-01)

Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway
由: Charles J. Malemud
出版: (2010-05-01)

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo
由: Seung Ho Shin, et al.
出版: (2017-11-01)

An inhibitor of RORγ for chronic pulmonary obstructive disease treatment
由: Harshada Desai, et al.
出版: (2022-05-01)

Small-Molecule Inhibitors of TIPE3 Protein Identified through Deep Learning Suppress Cancer Cell Growth In Vitro
由: Xiaodie Chen, et al.
出版: (2024-04-01)

A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model
由: Min-Ha Choi, et al.
出版: (2021-03-01)

Two small-molecule inhibitors of Toxoplasma gondii proliferation in vitro
由: Qian-qian Hua, et al.
出版: (2023-04-01)

ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy
由: Guilly eRebagay, et al.
出版: (2012-04-01)

Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis.
由: Chen, L, et al.
出版: (2015)

Small Molecule Inhibitors of Ceramidases
由: Essa M. Saied, et al.
出版: (2014-06-01)

CHARACTERIZING TYPE 17 IMMUNE RESPONSES IN ANKYLOSING SPONDYLITIS
由: Al-Mossawi, H, et al.
出版: (2013)

Immunoprecipitation of ROR1
由: Vincent Bicocca, et al.
出版: (2013-09-01)

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells
由: Anju Singh, et al.
出版: (2021-06-01)

Corrigendum: Two small-molecule inhibitors of Toxoplasma gondii proliferation in vitro
由: Qian-qian Hua, et al.
出版: (2023-12-01)

Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization
由: Julia Schanda, et al.
出版: (2017-05-01)

Variant Transcript of ROR1 ENST00000545203 Does Not Encode ROR1 Protein
由: Jie Xian, et al.
出版: (2024-07-01)

RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation
由: Amir Kumar Singh, et al.
出版: (2023-08-01)

AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity
由: Jefferson Antônio Leite, et al.
出版: (2023-11-01)

Pan-Tissue and -Cancer Analysis of ROR1 and ROR2 Transcript Variants Identify Novel Functional Significance for an Alternative Splice Variant of ROR1
由: Miya John, et al.
出版: (2022-10-01)

Altered Expression of STAT3, RORγt, and IL-17A Proteins and Th17 Cell in Intrahepatic Cholestasis of Pregnancy
由: Yu-Xia Wu, et al.
出版: (2022-07-01)

ROR1 Flow Cytometry
由: Vincent Bicocca, et al.
出版: (2013-09-01)