A model for effects of adaptive immunity on tumor response to chemotherapy and chemoimmunotherapy.
Complete clinical regressions of solid tumors in response to chemotherapy are difficult to explain by direct cytotoxicity alone, because of low growth fractions and obstacles to drug delivery. A plausible indirect mechanism that might reconcile this is the action of the immune system. A model for in...
Main Authors: | Robertson-Tessi, M, El-Kareh, A, Goriely, A |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Elsevier
2015
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