Pneumococcal conjugate and plain polysaccharide vaccines have divergent effects on antigen-specific B cells.

BACKGROUND: A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP), routinely administered at the age of 65, has limited effectiveness, and revaccination induces attenuated antibody responses. It is not known whether pneumococcal polysaccharide-protein conjugated vaccines (PCV), althou...

詳細記述

書誌詳細
主要な著者: Clutterbuck, E, Lazarus, R, Yu, L, Bowman, J, Bateman, E, Diggle, L, Angus, B, Peto, T, Beverley, P, Mant, D, Pollard, A
フォーマット: Journal article
言語:English
出版事項: 2012