Pneumococcal conjugate and plain polysaccharide vaccines have divergent effects on antigen-specific B cells.

BACKGROUND: A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP), routinely administered at the age of 65, has limited effectiveness, and revaccination induces attenuated antibody responses. It is not known whether pneumococcal polysaccharide-protein conjugated vaccines (PCV), althou...

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Những tác giả chính: Clutterbuck, E, Lazarus, R, Yu, L, Bowman, J, Bateman, E, Diggle, L, Angus, B, Peto, T, Beverley, P, Mant, D, Pollard, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2012