Corner cutting compromises clinical trials: the inherent problems with up-front randomisation and a common standard arm.
To minimise bias, clinical trials must be randomised, and all patients analysed by allocated treatment. With several separate randomisations, patients should be analysed only within the randomisation they entered, and not compared against patients in different randomisations. Some people worry that...
| Main Authors: | , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2003
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