Overexpression of Fto leads to increased food intake and results in obesity.
Genome-wide association studies have identified SNPs within FTO, the human fat mass and obesity-associated gene, that are strongly associated with obesity. Individuals homozygous for the at-risk rs9939609 A allele weigh, on average, ~3 kg more than individuals with the low-risk T allele. Mice that l...
| Main Authors: | , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2010
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