Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses.

Recent evidence demonstrating that exposure to rapamycin during viral infection increased the quantity and quality of Ag-specific T cells poses an intriguing paradox, because rapamycin is used in transplantation to dampen, rather than enhance, donor-reactive T cell responses. In this report, we comp...

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Bibliographic Details
Main Authors: Ferrer, I, Wagener, M, Robertson, J, Turner, A, Araki, K, Ahmed, R, Kirk, A, Larsen, C, Ford, M
Format: Journal article
Language:English
Published: 2010