The Mu subunit of Plasmodium falciparum Clathrin-associated adaptor protein 2 modulates in vitro parasite response to Artemisinin and Quinine
The emergence of drug-resistant parasites is a serious threat faced by malaria control programs. Understanding the genetic basis of resistance is critical to the success of treatment and intervention strategies. A novel locus associated with antimalarial resistance, ap2-mu (encoding the mu chain of...
المؤلفون الرئيسيون: | Henriques, G, van Schalkwyk, D, Burrow, R, Warhurst, D, Thompson, E, Baker, D, Fidock, D, Hallett, R, Flueck, C, Sutherland, C |
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التنسيق: | Journal article |
منشور في: |
American Society for Microbiology
2015
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مواد مشابهة
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The <italic toggle="yes">Plasmodium falciparum</italic> Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation
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Comparative effectiveness of artemisinin suppositories and oral quinine in children with acute falciparum malaria.
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Plasmodium falciparum malaria: rosettes are disrupted by quinine, artemisinin, mefloquine, primaquine, pyrimethamine, chloroquine and proguanil
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Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan children treated With ACT
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The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.
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