Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with Influenza A virus

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression, which have been shown to fine-tune innate immune responses downstream of pattern recognition receptor (PRR) signaling. This study identifies miR-650 as a novel PRR-responsive miRNA which is downregulated upon stimul...

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Những tác giả chính: Simmons, A, Pichulik, T, Khatamzas, E, Liu, X, Brain, O, Delmiro Garcia, M, Leslie, A, Danis, B, Mayer, A, Baban, D, Ragoussis, J, Weber, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Wiley 2016