Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis.
Fifty shigella strains were isolated from 700 diarrhoeal samples collected from adult diarrhoeal out-patients in Addis Ababa. Among the isolates, serogroup A comprised 28%, B 44%, C 18% and D 10%. Among all shigella serogroups, highest resistance was encountered to tetracycline (74%), ampicillin (70...
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Journal article |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
1997
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| _version_ | 1826272109209321472 |
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| author | Mache, A Mengistu, Y Cowley, S |
| author_facet | Mache, A Mengistu, Y Cowley, S |
| author_sort | Mache, A |
| collection | OXFORD |
| description | Fifty shigella strains were isolated from 700 diarrhoeal samples collected from adult diarrhoeal out-patients in Addis Ababa. Among the isolates, serogroup A comprised 28%, B 44%, C 18% and D 10%. Among all shigella serogroups, highest resistance was encountered to tetracycline (74%), ampicillin (70%), cephalothin (64%), trimethoprim-sulfamethoxazole (52%) and chloramphenicol (50%) while least resistance was observed to gentamicin (0%), polymyxin B (10%) and nalidixic acid (14%). Gentamicin, polymyxin B and nalidixic acid were found to be the drugs of choice for cases of shigellosis. All drug resistant isolates analysed for plasmids contained multiple plasmids ranging from 1.8 to greater than 21 Kilobases. |
| first_indexed | 2024-03-06T22:07:21Z |
| format | Journal article |
| id | oxford-uuid:509a7b1b-2021-4fc7-acbd-d5807e53ac83 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:07:21Z |
| publishDate | 1997 |
| record_format | dspace |
| spelling | oxford-uuid:509a7b1b-2021-4fc7-acbd-d5807e53ac832022-03-26T16:14:34ZShigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:509a7b1b-2021-4fc7-acbd-d5807e53ac83EnglishSymplectic Elements at Oxford1997Mache, AMengistu, YCowley, SFifty shigella strains were isolated from 700 diarrhoeal samples collected from adult diarrhoeal out-patients in Addis Ababa. Among the isolates, serogroup A comprised 28%, B 44%, C 18% and D 10%. Among all shigella serogroups, highest resistance was encountered to tetracycline (74%), ampicillin (70%), cephalothin (64%), trimethoprim-sulfamethoxazole (52%) and chloramphenicol (50%) while least resistance was observed to gentamicin (0%), polymyxin B (10%) and nalidixic acid (14%). Gentamicin, polymyxin B and nalidixic acid were found to be the drugs of choice for cases of shigellosis. All drug resistant isolates analysed for plasmids contained multiple plasmids ranging from 1.8 to greater than 21 Kilobases. |
| spellingShingle | Mache, A Mengistu, Y Cowley, S Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis. |
| title | Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis. |
| title_full | Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis. |
| title_fullStr | Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis. |
| title_full_unstemmed | Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis. |
| title_short | Shigella serogroups identified from adult diarrhoeal out-patients in Addis Ababa, Ethiopia: antibiotic resistance and plasmid profile analysis. |
| title_sort | shigella serogroups identified from adult diarrhoeal out patients in addis ababa ethiopia antibiotic resistance and plasmid profile analysis |
| work_keys_str_mv | AT machea shigellaserogroupsidentifiedfromadultdiarrhoealoutpatientsinaddisababaethiopiaantibioticresistanceandplasmidprofileanalysis AT mengistuy shigellaserogroupsidentifiedfromadultdiarrhoealoutpatientsinaddisababaethiopiaantibioticresistanceandplasmidprofileanalysis AT cowleys shigellaserogroupsidentifiedfromadultdiarrhoealoutpatientsinaddisababaethiopiaantibioticresistanceandplasmidprofileanalysis |