Evidence of early-stage selection on EPAS1 and GPR126 genes in Andean high altitude populations

Evidence of early-stage selection on EPAS1 and GPR126 genes in Andean high altitude populations

The aim of this study is to identify genetic variants that harbour signatures of recent positive selection and may facilitate physiological adaptations to hypobaric hypoxia. To achieve this, we conducted whole genome sequencing and lung function tests in 19 Argentinean highlanders (>3500 m) c...

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Bibliographic Details
Main Authors:	Eichstaedt, C, Pagani, L, Antao, T, Inchley, C, Cardona, A, Mörseburg, A, Clemente, F, Sluckin, T, Metspalu, E, Mitt, M, Mägi, R, Hudjashov, G, Metspalu, M, Mormina, M, Jacobs, G, Kivisild, T
Format:	Journal article
Language:	English
Published:	Nature Research 2017

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