Lysine methylation and the regulation of p53.
The p53 tumour suppressor protein functions as a guardian against genotoxic stress. This function is mediated in part by the transcriptional activation of genes involved in cell-cycle arrest, apoptosis, DNA repair and autophagy. The activity of p53 is regulated by a complex array of post-translation...
Main Authors: | Carr, S, Munro, S, La Thangue, N |
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Format: | Journal article |
Language: | English |
Published: |
2012
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