Lysine methylation and the regulation of p53.

The p53 tumour suppressor protein functions as a guardian against genotoxic stress. This function is mediated in part by the transcriptional activation of genes involved in cell-cycle arrest, apoptosis, DNA repair and autophagy. The activity of p53 is regulated by a complex array of post-translation...

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Hlavní autoři: Carr, S, Munro, S, La Thangue, N
Médium: Journal article
Jazyk:English
Vydáno: 2012