Transcription of subtelomerically located var gene variant in Plasmodium falciparum appears to require the truncation of an adjacent var gene.
The Plasmodium falciparum R29 clone preferentially transcribes the R29var gene variant on rosette selection, unlike other isogenic clones from the same parasite lineage. Characterisation of the R29var gene locus revealed that this gene lies internal to, and is in a tail-to-tail orientation with, a s...
Auteurs principaux: | Horrocks, P, Kyes, S, Pinches, R, Christodoulou, Z, Newbold, C |
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Format: | Journal article |
Langue: | English |
Publié: |
2004
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