Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis

Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic. To investigate this mechanism, we examined human lung tissue from 40 subjects with defined smoking status, with or without chronic o...

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Dades bibliogràfiques
Autors principals: Lugli, E, Correia, R, Fischer, R, Lundberg, K, Bracke, K, Montgomery, AB, Kessler, B, Brusselle, G, Venables, P
Format: Journal article
Idioma:English
Publicat: BioMed Central 2015