Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans.

Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans.

Hypoxia causes an increase in pulmonary artery pressure. Gene expression controlled by the hypoxia-inducible factor (HIF) family of transcription factors plays an important role in the underlying pulmonary vascular responses. The hydroxylase enzymes that regulate HIF are highly sensitive to varying...

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Bibliografiske detaljer
Main Authors:	Talbot, N, Croft, Q, Curtis, M, Turner, B, Dorrington, K, Robbins, P, Smith, T
Format:	Journal article
Sprog:	English
Udgivet:	2014

Lignende værker

Intravenous iron loading inhibits the pulmonary vascular response to hypoxia in humans
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Changes in pulmonary vascular responsiveness to hypoxia
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Human pulmonary vascular responses to hypoxia and hypercapnia.
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Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia
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The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
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