Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans.

Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans.

Hypoxia causes an increase in pulmonary artery pressure. Gene expression controlled by the hypoxia-inducible factor (HIF) family of transcription factors plays an important role in the underlying pulmonary vascular responses. The hydroxylase enzymes that regulate HIF are highly sensitive to varying...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Talbot, N, Croft, Q, Curtis, M, Turner, B, Dorrington, K, Robbins, P, Smith, T
Natura:	Journal article
Lingua:	English
Pubblicazione:	2014

Documenti analoghi

Intravenous iron loading inhibits the pulmonary vascular response to hypoxia in humans
di: Smith, T, et al.
Pubblicazione: (2007)

Changes in pulmonary vascular responsiveness to hypoxia
di: Talbot, NP, et al.
Pubblicazione: (2017)

Human pulmonary vascular responses to hypoxia and hypercapnia.
di: Dorrington, K, et al.
Pubblicazione: (2004)

Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia
di: Bart, N, et al.
Pubblicazione: (2016)

Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia
di: Bart, N, et al.
Pubblicazione: (2016)

The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
di: Smith, T, et al.
Pubblicazione: (2008)

Two temporal components within the human pulmonary vascular response to approximately 2 h of isocapnic hypoxia.
di: Talbot, N, et al.
Pubblicazione: (2005)

Time course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia.
di: Dorrington, K, et al.
Pubblicazione: (1997)

Time course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia
di: Dorrington, K, et al.
Pubblicazione: (1997)

Constancy of the human pulmonary circulatory response to 25 min eucapnic hypoxia in the presence of ventilatory adaptation
di: Talbot, N, et al.
Pubblicazione: (2002)

Iron chelation does not potentiate early acclimatisation to sustained hypoxia in humans
di: Talbot, N, et al.
Pubblicazione: (2007)

Intravenous iron and pulmonary hypertension in intensive care
di: Smith, T, et al.
Pubblicazione: (2011)

Intravenous iron and pulmonary hypertension in intensive care.
di: Smith, T, et al.
Pubblicazione: (2011)

Human pulmonary vascular responses to 25 min of euoxic hypercapnia and hypocapnia measured by Doppler echocardiography
di: Balanos, G, et al.
Pubblicazione: (2002)

Human pulmonary vascular response to 4 h of hypercapnia and hypocapnia measured using Doppler echocardiography.
di: Balanos, G, et al.
Pubblicazione: (2003)

Clinical iron deficiency disturbs normal human responses to hypoxia
di: Frise, M, et al.
Pubblicazione: (2016)

Changes in pulmonary vascular resistance in humans during isocapnic hypoxia measured non-invasively using Doppler echocardiography
di: Balanos, G, et al.
Pubblicazione: (2000)

Pulmonary and systemic vascular resistance during 8 h of isocapnic hypoxia in humans
di: Clar, C, et al.
Pubblicazione: (1997)

Release by hypoxia of a soluble vasoconstrictor from rabbit small pulmonary arteries.
di: Talbot, N, et al.
Pubblicazione: (2003)

Lack of involvement of the autonomic nervous system in early ventilatory and pulmonary vascular acclimatization to hypoxia in humans
di: Liu, C, et al.
Pubblicazione: (2007)

Lack of involvement of the autonomic nervous system in early ventilatory and pulmonary vascular acclimatization to hypoxia in humans.
di: Liu, C, et al.
Pubblicazione: (2007)

Extent to which pulmonary vascular responses to PCO2 and PO2 play a functional role within the healthy human lung.
di: Dorrington, K, et al.
Pubblicazione: (2010)

Effect of phosphoramidon on the acute response to hypoxia of rabbit isolated pulmonary arteries with and without endothelium
di: Talbot, N, et al.
Pubblicazione: (2001)

Intravenous endothelin-1 and ventilatory sensitivity to hypoxia in humans.
di: Talbot, N, et al.
Pubblicazione: (2008)

Hypoxic pulmonary vasoconstriction: Evidence in humans of a role for hypoxia inducible factor.
di: Balanos, G, et al.
Pubblicazione: (2001)

Changes in pulmonary vascular resistance in humans during euoxic hypercapnia and hypocapnia measured non-invasively using Doppler echocardiography
di: Balanos, G, et al.
Pubblicazione: (2001)

Pulmonary vascular response to air-breathing exercise in humans following an 8-h exposure to hypoxia.
di: Herigstad, M, et al.
Pubblicazione: (2009)

Variations in alveolar partial pressure for carbon dioxide and oxygen have additive not synergistic acute effects on human pulmonary vasoconstriction.
di: Croft, Q, et al.
Pubblicazione: (2013)

Human hypoxic pulmonary vasoconstriction is unaltered by 8 h of preceding isocapnic hyperoxia
di: Cheng, H, et al.
Pubblicazione: (2017)

Effect of low-dose enflurane on the ventilatory response to hypoxia in humans.
di: Nagyova, B, et al.
Pubblicazione: (1994)

Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
di: Balanos, G, et al.
Pubblicazione: (2002)

Intravenous iron delivers a sustained (8-week) lowering of pulmonary artery pressure during exercise in healthy older humans
di: Cheng, H, et al.
Pubblicazione: (2019)

Modulation of ventilatory sensitivity to hypoxia by dopamine and domperidone before and after prolonged exposure to hypoxia in humans
di: Pedersen, M, et al.
Pubblicazione: (1997)

Modulation of ventilatory sensitivity to hypoxia by dopamine and domperidone before and after prolonged exposure to hypoxia in humans.
di: Pedersen, M, et al.
Pubblicazione: (1998)

Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humans.
di: Balanos, G, et al.
Pubblicazione: (2005)

Dexamethasone mimics aspects of physiological acclimatization to 8 hours of hypoxia but suppresses plasma erythropoietin.
di: Liu, C, et al.
Pubblicazione: (2013)

Effects of haloperidol on ventilation during isocapnic hypoxia in humans.
di: Pedersen, M, et al.
Pubblicazione: (1997)

Effects of haloperidol on ventilation during isocapnic hypoxia in humans
di: Pedersen, M, et al.
Pubblicazione: (1996)

Effects of subanaesthetic sevoflurane on ventilation. 2: Response to acute and sustained hypoxia in humans.
di: Pandit, J, et al.
Pubblicazione: (1999)

Effect of 0.1 MAC sevoflurane on human ventilatory response to hypercapnia and hypoxia
di: Prandit, J, et al.
Pubblicazione: (1998)