Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans.

Hypoxia causes an increase in pulmonary artery pressure. Gene expression controlled by the hypoxia-inducible factor (HIF) family of transcription factors plays an important role in the underlying pulmonary vascular responses. The hydroxylase enzymes that regulate HIF are highly sensitive to varying...

Полное описание

Библиографические подробности
Главные авторы: Talbot, N, Croft, Q, Curtis, M, Turner, B, Dorrington, K, Robbins, P, Smith, T
Формат: Journal article
Язык:English
Опубликовано: 2014