Effect of mutation Arg91Gly on the thermal stability of β-tropomyosin

The mutation Arg91Gly (R91G) in β-tropomyosin (β-TM) is known to cause distal arthrogryposis, a severe congenital disorder of muscle tissues. The influence of this mutation in β-TM on its structure and thermal denaturation was demonstrated. It was shown by the differential scanning calorimetry and c...

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Autori principali: Nevzorov, I, Redwood, C, Levitsky, D
Natura: Journal article
Lingua:English
Pubblicazione: 2008