Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides.
A general strategy for the synthesis of 2-aryl-glycals and their elaboration to 2-C-aryl-α-glycosides and 1,5-anhydro-2-C-aryl-2-deoxy alditols are described. The use of reliable, efficient phosphine-free Suzuki-Miyaura cross-coupling of 2-iodoglycals in aqueous media as a key step proceeds with com...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2012
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| _version_ | 1826272205225328640 |
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| author | Cobo, I Matheu, M Castillón, S Boutureira, O Davis, B |
| author_facet | Cobo, I Matheu, M Castillón, S Boutureira, O Davis, B |
| author_sort | Cobo, I |
| collection | OXFORD |
| description | A general strategy for the synthesis of 2-aryl-glycals and their elaboration to 2-C-aryl-α-glycosides and 1,5-anhydro-2-C-aryl-2-deoxy alditols are described. The use of reliable, efficient phosphine-free Suzuki-Miyaura cross-coupling of 2-iodoglycals in aqueous media as a key step proceeds with complete regioselectivity at C-2 and enables access to 2-aryl-glycals with different configurations in excellent yields. |
| first_indexed | 2024-03-06T22:08:53Z |
| format | Journal article |
| id | oxford-uuid:511aa7d2-098c-41a5-bd7d-e32965c68535 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:08:53Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:511aa7d2-098c-41a5-bd7d-e32965c685352022-03-26T16:17:35ZPhosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:511aa7d2-098c-41a5-bd7d-e32965c68535EnglishSymplectic Elements at Oxford2012Cobo, IMatheu, MCastillón, SBoutureira, ODavis, BA general strategy for the synthesis of 2-aryl-glycals and their elaboration to 2-C-aryl-α-glycosides and 1,5-anhydro-2-C-aryl-2-deoxy alditols are described. The use of reliable, efficient phosphine-free Suzuki-Miyaura cross-coupling of 2-iodoglycals in aqueous media as a key step proceeds with complete regioselectivity at C-2 and enables access to 2-aryl-glycals with different configurations in excellent yields. |
| spellingShingle | Cobo, I Matheu, M Castillón, S Boutureira, O Davis, B Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. |
| title | Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. |
| title_full | Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. |
| title_fullStr | Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. |
| title_full_unstemmed | Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. |
| title_short | Phosphine-free Suzuki-Miyaura cross-coupling in aqueous media enables access to 2-C-aryl-glycosides. |
| title_sort | phosphine free suzuki miyaura cross coupling in aqueous media enables access to 2 c aryl glycosides |
| work_keys_str_mv | AT coboi phosphinefreesuzukimiyauracrosscouplinginaqueousmediaenablesaccessto2carylglycosides AT matheum phosphinefreesuzukimiyauracrosscouplinginaqueousmediaenablesaccessto2carylglycosides AT castillons phosphinefreesuzukimiyauracrosscouplinginaqueousmediaenablesaccessto2carylglycosides AT boutureirao phosphinefreesuzukimiyauracrosscouplinginaqueousmediaenablesaccessto2carylglycosides AT davisb phosphinefreesuzukimiyauracrosscouplinginaqueousmediaenablesaccessto2carylglycosides |