Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.

Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.

Regulatory T-cell (Treg) selection in the thymus is essential to prevent autoimmune diseases. Although important rules for Treg selection have been established, there is controversy regarding the degree of self-reactivity displayed by T-cell receptors expressed by Treg cells. In this study we have d...

Повний опис

Бібліографічні деталі
Автори: Lin, J, Yang, L, Silva, H, Trzeciak, A, Choi, Y, Schwab, S, Dustin, M, Lafaille, J
Формат: Journal article
Мова:English
Опубліковано: Nature Publishing Group 2016

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