Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.

Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.

Regulatory T-cell (Treg) selection in the thymus is essential to prevent autoimmune diseases. Although important rules for Treg selection have been established, there is controversy regarding the degree of self-reactivity displayed by T-cell receptors expressed by Treg cells. In this study we have d...

书目详细资料
Main Authors:	Lin, J, Yang, L, Silva, H, Trzeciak, A, Choi, Y, Schwab, S, Dustin, M, Lafaille, J
格式:	Journal article
语言:	English
出版:	Nature Publishing Group 2016

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