The C-terminal extension landscape of naturally presented HLA-I ligands

HLA-I molecules play a central role in antigen presentation. They typically bind 9- to 12-mer peptides, and their canonical binding mode involves anchor residues at the second and last positions of their ligands. To investigate potential noncanonical binding modes, we collected in-depth and accurate...

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Bibliographic Details
Main Authors: Guillaume, P, Picaud, S, Baumgaertner, P, Montandon, N, Schmidt, J, Speiser, D, Coukos, G, Bassani-Sternberg, M, Filippakopoulos, P, Gfeller, D
Format: Journal article
Language:English
Published: National Academy of Sciences 2018