A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism.

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism.

Foxp3(+) regulatory T (T reg) cells play a key role in controlling immune pathological re actions. Many develop their regulatory activity in the thymus, but there is also evidence for development of Foxp3(+) T reg cells from naive precursors in the periphery. Recent studies have shown that transform...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coombes, J, Siddiqui, K, Arancibia-Cárcamo, C, Hall, J, Sun, C, Belkaid, Y, Powrie, F
Formato:	Journal article
Lenguaje:	English
Publicado:	2007

Ejemplares similares

The contribution of Foxp3 and TGF beta to the iTreg proteome
por: Howie, D, et al.
Publicado: (2013)

Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation.
por: Izcue, A, et al.
Publicado: (2006)

Expression and regulation of the TGF-beta-activating integrin alpha(v)beta(8) on human dendritic cells
por: Fenton, T, et al.
Publicado: (2013)

Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection.
por: Walther, M, et al.
Publicado: (2005)

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells.
por: Fahlén, L, et al.
Publicado: (2005)

Anti-inflammatory peripheral adenosine generation by leukocytes is tightly regulated by TGF-beta and is independent of Foxp3
por: Regateiro, F, et al.
Publicado: (2010)

FOXP3+ regulatory T cells: Current controversies and future perspectives.
por: Banham, A, et al.
Publicado: (2006)

The role of FoxP3(+) regulatory T-cells in psoriasiform skin disease
por: Adelmann, K, et al.
Publicado: (2014)

Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma
por: Zimmerman, Mark W, et al.
Publicado: (2023)

Distribution of transforming growth factor-beta isoforms TGF-beta 1, TGF-beta 2 and TGF-beta 3 and vascular endothelial growth factor in vulvar lichen sclerosus.
por: Farrell, A, et al.
Publicado: (2001)

Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection.
por: Moore, C, et al.
Publicado: (2015)

Cartilage injury suppresses endogenous retinoic acid through activation of TGFβ-activated kinase 1 (TAK1)
por: Zhu, L, et al.
Publicado: (2018)

Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
por: Izcue, A, et al.
Publicado: (2008)

Involvement of TGF-beta in skin photoaging
por: Choi, Won Seon, 1975-
Publicado: (2008)

Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.
por: Knosp, C, et al.
Publicado: (2013)

Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naive T cells in dendritic cell clustering.
por: Chen, Y, et al.
Publicado: (2012)

Special regulatory T-cell review: Regulatory T cells and the intestinal tract--patrolling the frontier.
por: Izcue, A, et al.
Publicado: (2008)

MIG and the regulatory cytokines IL-10 and TGF-[beta]1 correlate with malaria vaccine immunogenicity and efficacy.
por: Dunachie, S, et al.
Publicado: (2010)

Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells.
por: Laffont, S, et al.
Publicado: (2010)

CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria.
por: Barnes, M, et al.
Publicado: (2013)

Modulation of human osteoprogenitor cell differentiation by 9-CIS retinoic acid and retinoic acid
por: Oreffo, R, et al.
Publicado: (1997)

Regulatory lymphocytes and intestinal inflammation.
por: Izcue, A, et al.
Publicado: (2009)

Harnessing FOXP3+ regulatory T cells for transplantation tolerance.
por: Waldmann, H, et al.
Publicado: (2014)

FOXP3+ regulatory T cells as biomarkers in human malignancies.
por: Bignone, P, et al.
Publicado: (2008)

The role of Foxp3+ regulatory T-cells in transplant tolerance
por: Kendal, A, et al.
Publicado: (2011)

Interleukin 7 signaling on DCs regulates the CD 4 T cell niche
por: Fewkes, N, et al.
Publicado: (2011)

Altered expression of TGF alpha and TGF beta 1 in the mucosa of the functioning pelvic ileal pouch.
por: Campbell, A, et al.
Publicado: (1996)

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.
por: Miyao, T, et al.
Publicado: (2012)

The FOXP3 transcription factor as a regulatory T-cell marker
por: Banham, A
Publicado: (2008)

TGF-beta and graft vasculopathy: where to from here?
por: Bushell, A
Publicado: (2002)

Inhibition of Immune-suppressive TGF beta in Tumour Models
por: Alamoudi, A, et al.
Publicado: (2011)

The role of retinoic acid in cartilage mechanoflammation
por: Kamalathevan, P
Publicado: (2022)

Pioneer DCS gets update /
por: 420512 Blickley, George J.

Phosphorylation and activation of transforming growth factor beta (TGF-[beta]) receptor kinases
por: Chen, Feng
Publicado: (2008)

Therapeutic targeting of FOXP3-positive regulatory T cells using a FOXP3 peptide vaccine WO2008081581.
por: Banham, A, et al.
Publicado: (2009)

Inhibition of adipogenesis and modulation of human bone marrow osteoprogenitor differentiation by 9-cis retinoic acid and retinoic acid.
por: Oreffo, R, et al.
Publicado: (1997)

The role of mucosal T lymphocytes in regulating intestinal inflammation.
por: Uhlig, H, et al.
Publicado: (2005)

The balance between conventional DCs and plasmacytoid DCs is pivotal for immunological tolerance during pregnancy in the mouse
por: Shi, Meng, et al.
Publicado: (2018)

Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase.
por: Zhou, L, et al.
Publicado: (2011)

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease.
por: Saruta, M, et al.
Publicado: (2007)