RAS-Mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines.

The expression of activated RAS oncogenes has been shown to increase radioresistance in a number of cell lines. The pathways by which RAS leads to radioresistance, however, are unknown. RAS activates several signal transduction pathways, with the RAF-MAP2K-MAP kinase pathway perhaps the best studied...

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Príomhchruthaitheoirí: Gupta, A, Bernhard, E, Bakanauskas, V, Wu, J, Muschel, R, Mckenna, W
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2000