RNA replication kinetics, genetic polymorphism and selection in the case of the hepatitis C virus.
We show in a simple theoretical quasispecies model that the replication dynamics of hepatitis C virus and a related model-system, the bovine viral diarrhoea virus, result in an effective reduction of RNA templates in infected cells. Viral fitness does not translate directly into RNA sequence replica...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Royal Society
2001
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