Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up

<h4>Purpose</h4> <p>Whilst medial UKR is indicated for full-thickness cartilage loss (FTCL) on occasion it has been used to treat partial-thickness cartilage loss (PTCL). This matched case-control study investigates the five-year outcomes in a consecu...

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Main Authors: Hamilton, T, Pandit, H, Inabathula, A, Ostlere, S, Jenkins, C, Mellon, S, Dodd, C, Murray, D
Format: Journal article
Published: British Editorial Society of Bone and Joint Surgery 2017
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author Hamilton, T
Pandit, H
Inabathula, A
Ostlere, S
Jenkins, C
Mellon, S
Dodd, C
Murray, D
author_facet Hamilton, T
Pandit, H
Inabathula, A
Ostlere, S
Jenkins, C
Mellon, S
Dodd, C
Murray, D
author_sort Hamilton, T
collection OXFORD
description <h4>Purpose</h4> <p>Whilst medial UKR is indicated for full-thickness cartilage loss (FTCL) on occasion it has been used to treat partial-thickness cartilage loss (PTCL). This matched case-control study investigates the five-year outcomes in a consecutive series of UKR implanted for PTCL.</p> <h4>Methods</h4> <p>Between 2002 and 2014, 94consecutive UKR (90patients) were implanted by two surgeons for PTCL and followed up independently for a mean 6years (range 1-13). These cases were matched 1:2 based on age, gender and preoperative OKS with knees with FTCL anteromedial osteoarthritis managed with UKR. Functional outcomes, implant survival and incidence of reoperations was assessed at one, two and five years. A sub-study of 36knees (36patients) with PTCL who had had pre-operative MRI was performed to identify whether there were any MRI factors that predicted outcomes. </p> <h4>Results</h4> <p>Knees with PTCL had significantly worse functional outcomes (OKS and AKSS-O) at one, two and five years postoperatively. A quarter of knees with PTCL reported fair or poor results and a fifth failed to achieve a clinically significant improvement from baseline of four points or more on the OKS, double that seen in knees with FTCL. Whilst no difference in implant survival was detected between groups, knees with PTCL had a triple the reoperation rate with the majority, three-quarters, being arthroscopies for persistent pain. </p> <br/> <p>Patients with PTCL who achieved fair or poor outcomes were younger with worse preoperative functional scores, compared to those who achieve good or excellent outcomes however no other differences in baseline demographics were seen. MRI findings (FTCL, subchondral oedema, synovitis or effusion) did not provide additional prognostic information. </p> <h4>Conclusion</h4> <p>Medial UKR should be reserved for patients with FTCL, whilst some patients with PTCL do achieve good results, at present, we cannot identify which these will be and in this situation MRI is not only unhelpful but also misleading. </p>
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spelling oxford-uuid:51776da0-c72f-40c2-9554-791fe4ffa1f92022-03-26T16:19:47ZUnsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-upJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:51776da0-c72f-40c2-9554-791fe4ffa1f9Symplectic Elements at OxfordBritish Editorial Society of Bone and Joint Surgery2017Hamilton, TPandit, HInabathula, AOstlere, SJenkins, CMellon, SDodd, CMurray, D <h4>Purpose</h4> <p>Whilst medial UKR is indicated for full-thickness cartilage loss (FTCL) on occasion it has been used to treat partial-thickness cartilage loss (PTCL). This matched case-control study investigates the five-year outcomes in a consecutive series of UKR implanted for PTCL.</p> <h4>Methods</h4> <p>Between 2002 and 2014, 94consecutive UKR (90patients) were implanted by two surgeons for PTCL and followed up independently for a mean 6years (range 1-13). These cases were matched 1:2 based on age, gender and preoperative OKS with knees with FTCL anteromedial osteoarthritis managed with UKR. Functional outcomes, implant survival and incidence of reoperations was assessed at one, two and five years. A sub-study of 36knees (36patients) with PTCL who had had pre-operative MRI was performed to identify whether there were any MRI factors that predicted outcomes. </p> <h4>Results</h4> <p>Knees with PTCL had significantly worse functional outcomes (OKS and AKSS-O) at one, two and five years postoperatively. A quarter of knees with PTCL reported fair or poor results and a fifth failed to achieve a clinically significant improvement from baseline of four points or more on the OKS, double that seen in knees with FTCL. Whilst no difference in implant survival was detected between groups, knees with PTCL had a triple the reoperation rate with the majority, three-quarters, being arthroscopies for persistent pain. </p> <br/> <p>Patients with PTCL who achieved fair or poor outcomes were younger with worse preoperative functional scores, compared to those who achieve good or excellent outcomes however no other differences in baseline demographics were seen. MRI findings (FTCL, subchondral oedema, synovitis or effusion) did not provide additional prognostic information. </p> <h4>Conclusion</h4> <p>Medial UKR should be reserved for patients with FTCL, whilst some patients with PTCL do achieve good results, at present, we cannot identify which these will be and in this situation MRI is not only unhelpful but also misleading. </p>
spellingShingle Hamilton, T
Pandit, H
Inabathula, A
Ostlere, S
Jenkins, C
Mellon, S
Dodd, C
Murray, D
Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up
title Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up
title_full Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up
title_fullStr Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up
title_full_unstemmed Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up
title_short Unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss: a medium-term follow-up
title_sort unsatisfactory outcomes following unicompartmental knee replacement for partial thickness cartilage loss a medium term follow up
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AT inabathulaa unsatisfactoryoutcomesfollowingunicompartmentalkneereplacementforpartialthicknesscartilagelossamediumtermfollowup
AT ostleres unsatisfactoryoutcomesfollowingunicompartmentalkneereplacementforpartialthicknesscartilagelossamediumtermfollowup
AT jenkinsc unsatisfactoryoutcomesfollowingunicompartmentalkneereplacementforpartialthicknesscartilagelossamediumtermfollowup
AT mellons unsatisfactoryoutcomesfollowingunicompartmentalkneereplacementforpartialthicknesscartilagelossamediumtermfollowup
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AT murrayd unsatisfactoryoutcomesfollowingunicompartmentalkneereplacementforpartialthicknesscartilagelossamediumtermfollowup