The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.
MicroRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression through binding to messenger RNAs (mRNA) thereby promoting mRNA degradation or altered translation. A single-nucleotide polymorphism (SNP) located within a miRNA-binding site could thus alter mRNA translation and i...
Main Authors: | Teo, M, Landi, D, Taylor, C, Elliott, F, Vaslin, L, Cox, D, Hall, J, Landi, S, Bishop, D, Kiltie, A |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2012
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