The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.

MicroRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression through binding to messenger RNAs (mRNA) thereby promoting mRNA degradation or altered translation. A single-nucleotide polymorphism (SNP) located within a miRNA-binding site could thus alter mRNA translation and i...

Podrobná bibliografie
Hlavní autoři:	Teo, M, Landi, D, Taylor, C, Elliott, F, Vaslin, L, Cox, D, Hall, J, Landi, S, Bishop, D, Kiltie, A
Médium:	Journal article
Jazyk:	English
Vydáno:	2012

Podobné jednotky

MicroRNA binding site polymorphisms as biomarkers in cancer management and research
Autor: Cipollini M, a další
Vydáno: (2014-07-01)

DNA repair gene XRCC1 polymorphisms and bladder cancer risk
Autor: Sak, S, a další
Vydáno: (2007)

MRE11 variants as predictive markers of radiotherapy response in muscle invasive bladder cancer
Autor: Teo, M, a další
Vydáno: (2012)

DNA repair gene <it>XRCC1 </it>polymorphisms and bladder cancer risk
Autor: Bishop D Timothy, a další
Vydáno: (2007-04-01)

Comprehensive analysis of 22 XPC polymorphisms and bladder cancer risk.
Autor: Sak, S, a další
Vydáno: (2006)

Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.
Autor: Stern, M, a další
Vydáno: (2009)

Molecular epidemiology of DNA repair genes in bladder cancer.
Autor: Kiltie, A
Vydáno: (2009)

Functional assays to determine the significance of two common XPC 3'UTR variants found in bladder cancer patients.
Autor: Qiao, B, a další
Vydáno: (2011)

DNA repair gene XPC polymorphisms, smoking, occupational exposures and the risk of bladder transitional cell carcinoma
Autor: Sak, S, a další
Vydáno: (2005)

MRE11 expression is predictive of cause-specific survival following radical radiotherapy for muscle-invasive bladder cancer.
Autor: Choudhury, A, a další
Vydáno: (2010)

Using gene polymorphisms to assess bladder cancer risk: progress and challenges.
Autor: Kiltie, A
Vydáno: (2012)

Using gene polymorphisms to assess bladder cancer risk: Progress and challenges
Autor: Kiltie, A
Vydáno: (2012)

Functional assays to determine the significance of two common <it>XPC </it>3'UTR variants found in bladder cancer patients
Autor: Bishop D, a další
Vydáno: (2011-06-01)

Analysis of variants in DNA damage signalling genes in bladder cancer
Autor: Choudhury, A, a další
Vydáno: (2008)

Next-generation sequencing identifies germline MRE11A variants as markers of radiotherapy outcomes in muscle-invasive bladder cancer
Autor: Teo, M, a další
Vydáno: (2014)

A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer.
Autor: Junhua Luo, a další
Vydáno: (2012-01-01)

High MRE11 expression in muscle invasive bladder cancer is predictive of improved cause-specific survival following radical radiotherapy compared to surgery
Autor: Teo, T, a další
Vydáno: (2010)

In vitro functional effects of XPC gene rare variants from bladder cancer patients.
Autor: Qiao, B, a další
Vydáno: (2011)

Analysis of variants in DNA damage signalling genes in bladder cancer
Autor: Bishop D Timothy, a další
Vydáno: (2008-07-01)

Common predisposition alleles for moderately common cancers: bladder cancer.
Autor: Kiltie, A
Vydáno: (2010)

The role of microRNAs in bladder cancer
Autor: Hideki Enokida, a další
Vydáno: (2016-06-01)

RAD51: A DNA repair target for increasing the therapeutic potential in bladder cancer
Autor: Choudhury, A, a další
Vydáno: (2005)

APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer.
Autor: Sak, S, a další
Vydáno: (2005)

Single Nucleotide Polymorphisms in MicroRNA Binding Sites: Implications in Colorectal Cancer
Autor: Panchalee Bhaumik, a další
Vydáno: (2014-01-01)

The polyAT, intronic IVS11-6 and Lys939Gln XPC polymorphisms are not associated with transitional cell carcinoma of the bladder.
Autor: Sak, S, a další
Vydáno: (2005)

MRE11 as a predictive biomarker of outcome following radiotherapy in bladder cancer
Autor: Walker, AK, a další
Vydáno: (2019)

Phase II study of conformal hypofractionated radiotherapy with concurrent gemcitabine in muscle-invasive bladder cancer.
Autor: Choudhury, A, a další
Vydáno: (2011)

Gemcitabine as a Chemoradiosensitiser in Bladder Cancer
Autor: Kerr, M, a další
Vydáno: (2012)

Mechanisms of microRNA action in rectal cancer radiotherapy
Autor: Lili Zhu, a další
Vydáno: (2022-09-01)

Predictive Biomarkers for Gemcitabine as a Chemoradiosensitizer in Bladder Cancer
Autor: Kerr, M, a další
Vydáno: (2012)

Single nucleotide polymorphisms at the microRNA-binding site of KIAA0423 are associated with colorectal cancer
Autor: Yue Zhao, a další
Vydáno: (2016-11-01)

A multicentre NCRI phase II study of hypofractionated conformal radiotherapy with concurrent gemcitabine in muscle-invasive bladder cancer
Autor: Choudhury, A, a další
Vydáno: (2010)

Utility of bladder-sparing therapy vs radical cystectomy for muscle-invasive bladder cancer
Autor: Efstathiou, J, a další
Vydáno: (2018)

Feasibility of magnetic resonance guided radiotherapy for the treatment of bladder cancer
Autor: A. Hunt, a další
Vydáno: (2020-11-01)

Imatinib radiosensitizes bladder cancer by targeting homologous recombination.
Autor: Qiao, B, a další
Vydáno: (2013)

DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining.
Autor: Bentley, J, a další
Vydáno: (2004)

Polymorphisms of microRNA sequences or binding sites and lung cancer: a meta-analysis and systematic review.
Autor: Zhiwei Chen, a další
Vydáno: (2013-01-01)

MicroRNA related polymorphisms and breast cancer risk.
Autor: Sofia Khan, a další
Vydáno: (2014-01-01)

Comparison of treatment outcome for radical surgery versus radical radiotherapy for invasive bladder cancer treated in a UK specialist treatment centre
Autor: Kotwal, S, a další
Vydáno: (2007)

Similar treatment outcomes for radical cystectomy and radical radiotherapy in invasive bladder cancer treated at a United Kingdom specialist treatment center.
Autor: Kotwal, S, a další
Vydáno: (2008)